[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] a-Neo-Endorphin (1-7) CAS NO.80237-40-7

[Met5, Lys6,7] α-Neo-Endorphin (1-7) is a synthetic heptapeptide analog derived from the endogenous opioid α-Neoendorphin, featuring key amino acid substitutions at positions 5, 6, and 7 (Met, Lys, Lys). This modification is designed to enhance peptide stability and alter receptor interaction profiles compared to the native sequence. It is primarily utilized in biochemical repesquisa as a tool compound for investigating opioid receptor signaling, structure-activity relationships (SAR), and pain modulation pathways, strictly for repesquisa purposes.


TECHNICAL SPECIFICATIONS


Item
Specification
PRODUTO Nome
[Met5, Lys6,7] a-Neo-Endorphin (1-7)
CAS NO.
80237-40-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C₃₉H₅₉N₉O₉S
Molecular Weight
849.0g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Potent agonist for mu and kappa opioid receptors; modulates pain perception and neurotransmitter release
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Localização
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide retains the conserved N-terminal Tyr-Gly-Gly-Phe motif essential for opioid receptor engagement. It functions as a ligand for G protein-coupled opioid receptors (primarily μ and κ subtypes), activating inhibitory G proteins upon binding. This interaction triggers a cascade that reduces adenylate cyclase activity and cAMP PRODUTOion, leading to neuronal hyperpolarization and inhibition of neurotransmitter release, which underlies its potential modulatory effects on pain perception and neuronal excitability.

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2.PRODUTO INDICATIONS

This PRODUTO is indicated for Repesquisa Use Only (RUO), targeting academic institutions, pharmaceutical R&D departments, and biotech repesquisaers focused on neuropharmacology. It is applied in in vitro receptor binding assays, functional cell-based studies, and animal model experiments to elucidate the role of opioid systems in analgesia, addiction, and neuropsychiatric disorders. It is not intended for diagnostic or therapeutic use in humans.

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3.CLINICAL EFFICACY OF PRODUTO

While not approved for clinical use, experimental data from preclinical studies suggest that this analog exhibits bioactive properties characteristic of opioid peptides, including potential analgesic and behavioral effects in animal models. Its efficacy is primarily demonstrated in repesquisa settings for validating receptor targets and screening novel therapeutic candidates, with no established human clinical trial data.

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4.Certificado

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Produtos, adhering strictly to quality standards and obtaining internationTodosy recognized Certificaçãos.


O NOSSO PRODUTOion partners Todos employ GMP-compliant PRODUTOion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODUTO comes with complete documentation, including a Certificado of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and repesquisa-grade peptide Produtos to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging SOLUÇÃO to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODUTO.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODUTOion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The Empresa invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Certificaçãos, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Produtos and superior services.


We focus on the repesquisa and development and supply of high-quality chemical Produtos, strictly adhering to international standards and quality systems. O NOSSO PRODUTOs are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific repesquisa, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Etiquetas: Met5Lys6,7AlphaNeoEndorphin, #AlphaNeoendorphinAnalog, #OpioidPeptide, #KappaOpioidReceptor, #MuOpioidReceptor, #PainRepesquisa, #NeuropharmacologyReagent, #SyntheticOpioid, #RepesquisaPeptide, #StructureActivityRelationship, #AnalgesiaRepesquisa, #GPCRAgonist, #NeuroscienceTool, #RUOPeptide, #BiochemicalReagent

If you have any PRODUTO requirements, please an E-mail to:support@huanqiukeji9.com;Enviar:85244969439

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