[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]-γ-Endorphin is a naturTodosy occurring neuropeptide fragment derived from β-Endorphin, specificTodosy lacking the N-terminal tyrosine residue (position 1). This unique truncation eliminates its Classeical opioid analgesic activity while retaining significant neuropsychiatric effects. It is primarily utilized in neuroscience repesquisa as a critical tool compound for studying non-opioid pathways related to mental health disorders, stress responses, and neuroendocrine regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
PRODUTO Nome
[Des-Tyr1]- g-Endorphin 
CAS NO.
67810-56-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₇₄H₁₂₂N₁₈O₂₅S
Molecular Weight
1747.9g/mol
Purity (RP-HPLC)
≥95% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Modulates dopaminergic and serotonergic neurotransmission; non-opioid neuroleptic effects
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Localização
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Unlike full-length endorphins, this peptide does not bind significantly to μ-opioid receptors due to the missing Tyr1 moiety. Instead, it exerts its effects through non-opioid mechanisms, primarily by modulating central dopaminergic and serotonergic neurotransmission. It acts as a neuroleptic-like agent, reducing dopamine release in the mesolimbic pathway and influencing GABAergic and glutamatergic systems, which underlies its observed behavioral effects in animal models.

upload/attachment/image/202604/30/177751451944d44e3d91d3d18226d69c9ebd399bf8_local.pngupload/attachment/image/202604/30/1777514546b2ec0b004c089f7e4546f5a417497f9f_local.png

2.PRODUTO INDICATIONS

This PRODUTO is intended for Repesquisa Use Only (RUO), targeting academic and pharmaceutical repesquisaers in psychiatry and neuropharmacology. It is indicated for in vitro binding assays and in vivo studies investigating schizophrenia-like symptoms, depression, addiction, and reward pathways. It serves as an essential reference standard for elucidating the role of endorphin fragments in psychiatric pathophysiology.

upload/attachment/image/202604/30/177751457214e1c7dfc148c0af3c1f5917246c0316_local.png

3.CLINICAL EFFICACY OF PRODUTO

While not approved for human therapy, historical experimental data from smTodos-scale human studies and extensive animal repesquisa suggest potential efficacy in reducing psychotic symptoms and improving mood-related behaviors. Its neuroleptic-like profile has shown promise in modulating maladaptive behaviors associated with dopamine dysregulation, providing a rationale for its use in preclinical drug discovery.

upload/attachment/image/202604/30/1777514618acc216dbe545770688e6c0eb606a6f16_local.png

4.Certificado

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Produtos, adhering strictly to quality standards and obtaining internationTodosy recognized Certificaçãos.


O NOSSO PRODUTOion partners Todos employ GMP-compliant PRODUTOion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODUTO comes with complete documentation, including a Certificado of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and repesquisa-grade peptide Produtos to our global partners.

upload/attachment/image/202603/30/17748488791d02f82103a700e61eeafa024a96f6ff_local.jpg

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging SOLUÇÃO to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODUTO.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg


Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODUTOion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The Empresa invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Certificaçãos, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Produtos and superior services.


We focus on the repesquisa and development and supply of high-quality chemical Produtos, strictly adhering to international standards and quality systems. O NOSSO PRODUTOs are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific repesquisa, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Etiquetas: DesTyr1GammaEndorphin, #DTgammaE, #GammaEndorphinAnalog, #NeurolepticPeptide, #NonOpioidEndorphin, #DopamineModulator, #PsychiatricRepesquisa, #SchizophreniaRepesquisa, #BetaEndorphinDerivative, #NeuropeptideRepesquisa, #BehavioralNeuroscience, #RUOPeptide, #NeuropharmacologyReagent, #RepesquisaChemical

If you have any PRODUTO requirements, please an E-mail to:support@huanqiukeji9.com;Enviar:85244969439

Glutationa ganha atenção global à medida que ciência, bem-estar e regulamentação convergem
Jan 07, 26
Glutationa ganha atenção global à medida que ciência, bem-estar e regulamentação convergem

A glutationa, muitas vezes referida como o “antioxidante mestre” do corpo, passou da relativa obscuridade nos livros médicos para o centro da discussão global em saúde, bem-estar e biotecnologia. Uma vez conhecida principalmente por investigadores e médicos, esta molécula natural é agora amplamente discutida em contextos que vão desde a investigação de doenças crónicas até tendências de cuidados de pele e suplementos dietéticos. À medida que o interesse continua a crescer, cientistas, reguladores e consumidores estão reexaminando o que é a glutationa, o que pode fazer e como deve ser utilizada de forma responsável.

Dianabol (methandienona) permanece no centro do debate global sobre medicamentos que melhoram o desempenho
Jan 07, 26
Dianabol (methandienona) permanece no centro do debate global sobre medicamentos que melhoram o desempenho

Com o aprofundamento da implementação da estratégia "Made in China 2025" e o rápido avanço na fabricação de equipamentos de alta qualidade, a indústria de acoplamentos da China está acelerando sua transformação em direção ao desenvolvimento inTelefoneigente e orientado para a precisão. 

Preocupações crescentes cercam o mercado ilícito de esteróides anabolizantes, óleo Dianabol
Jan 07, 26
Preocupações crescentes cercam o mercado ilícito de esteróides anabolizantes, óleo Dianabol

A conversa global sobre drogas que melhoram o desempenho intensificou-se mais uma vez à medida que os esteróides anabolizantes, particularmente produtos comercializados como óleo Dianabol, continuam a surgir em mercados ilegais. Dianabol, cientificamente conhecido como metandrostenolona, ​​é um dos esteróides anabolizantes mais conhecidos na história do fisiculturismo. Originalmente desenvolvido em meados do século XX para uso médico, há muito que se tornou controverso devido ao uso indevido generalizado, aos riscos para a saúde e às repressões regulamentares.

Se você estiver interessado em nossos produtos, você pode escolher deixar suas informações aqui, e estaremos em contato com você em breve.