β-Endorphin (1-27), human CAS NO.76622-84-9

β-Endorphin (1-27), human is a naturTodosy occurring N-terminal fragment of the full-length β-endorphin peptide, functioning as a potent endogenous opioid receptor antagonist. Unlike many analgesic peptides, it competitively binds to μ-, δ-, and κ-opioid receptors to block signaling, making it a critical repesquisa tool for studying pain modulation, receptor dynamics, and the endogenous opioid system in neuroscience and pharmacology laboratories.

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TECHNICAL SPECIFICATIONS

Item	Specification
PRODUTO Nome	β-Endorphin (1-27), human
CAS NO.	76622-84-9
Appearance	White to off-white lyophilized powder
Molecular Formula	C₁₃₉H₂₁₇N₃₃O₄₀S
Molecular Weight	3180.5g/mol
Purity (RP-HPLC)	≥95%
Solubility	Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin	≤1 EU/mg
Biological Activity	Potent antagonist at μ, δ, and κ opioid receptors
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Localização	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Endomorphin-2 exerts its effects by selectively binding to μ-opioid receptors with high affinity, thereby activating G-protein coupled signaling pathways that inhibit adenylate cyclase and reduce cAMP PRODUTOion. This action leads to the hyperpolarization of neurons and inhibition of neurotransmitter release, effectively blocking pain signal transmission in both the central and peripheral nervous systems. Its mechanism is distinct in its ability to induce the release of other endogenous opioids like dynorphin A, contributing to its complex analgesic profile in preclinical models.

2.PRODUTO INDICATIONS

This PRODUTO is strictly indicated for repesquisa use in biochemical and pharmacological studies, including receptor binding assays, signal transduction repesquisa, and in vitro functional characterization of μ-opioid receptor activity. It is particularly valuable for scientists investigating spinal cord-mediated analgesia, neuropathic pain mechanisms, and opioid receptor pharmacology. The peptide is also employed in the screening and development of new analgesic drugs and in studies exploring the physiological roles of endogenous opioid systems.

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3.CLINICAL EFFICACY OF PRODUTO

As a repesquisa biochemical, β-Endorphin (1-27) is not intended for human therapeutic use. Its efficacy is demonstrated in preclinical repesquisa settings, where it has been shown to effectively reverse or Anteriorent analgesia induced by full-length β-endorphin and other opioid agonists in animal models, providing robust data on the modulation of nociceptive thresholds and the physiological role of endogenous opioid fragments.

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4.Certificado

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Produtos, adhering strictly to quality standards and obtaining internationTodosy recognized Certificaçãos.

O NOSSO PRODUTOion partners Todos employ GMP-compliant PRODUTOion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODUTO comes with complete documentation, including a Certificado of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and repesquisa-grade peptide Produtos to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging SOLUÇÃO to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODUTO.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODUTOion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The Empresa invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Certificaçãos, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Produtos and superior services.

We focus on the repesquisa and development and supply of high-quality chemical Produtos, strictly adhering to international standards and quality systems. O NOSSO PRODUTOs are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific repesquisa, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Etiquetas: BetaEndorphin127, #OpioidReceptorAntagonist, #EndogenousOpioid, #PainRepesquisa, #NeuroscienceReagent, #PeptideAntagonist, #MuDeltaKappaOpioid, #RepesquisaPeptide, #Neuropharmacology, #CAS76622849

If you have any PRODUTO requirements, please an E-mail to:support@huanqiukeji9.com;Enviar:85244969439

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